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Piperacillin → Piperacillin 2-acetamido-2-deoxy-N-(1-amino-(R/S)-dodecoyl)-beta-D-gluco-pyranosylamine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Piperacillin | HCID 43672 | — |
| 反応物 | 2-acetamido-2-deoxy-N-(1-amino-(R/S)-dodecoyl)-beta-D-glucopyranosylamine | HCID 131726725 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 生成物 | Piperacillin 2-acetamido-2-deoxy-N-(1-amino-(R/S)-dodecoyl)-beta-D-gluco-pyranosylamine | HCID 131726724 | 97% |
反応手順
Piperacillin (2.00 g, 3.87 mmol) and 2-acetamido-2-deoxy-N-(1-amino-(R/S)-dodecoyl)-β-D-glucopyranosylamine (32) (1.61 g, 3.87 mmol) were dissolved in 95% acetic acid. Once fully dissolved, the solution was filtered and lyophilised to give (35) as a white solid (3.50 g, 97%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07312194B2 |
| 出典データセット | uspto-grants-2007_12 |
| ORD ID | ord-687e629e145f4b0997f44d0314ac4f67 |
| 出典メモ | uspto-grants-2007_12 |