化工社化工社 化学情報印刷レポート · 研究参考用
2-Acetamidobenzyl alcohol → N-(2-formylphenyl)acetamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Acetamidobenzyl alcohol | HCID 339292 | — |
| 触媒 | Manganese dioxide | HCID 14801 | — |
| 溶媒 | Chloroform | HCID 6212 | — |
| 生成物 | N-(2-formylphenyl)acetamide | HCID 326664 | 73% |
反応手順
To a stirred solution of N-acetyl-2-amino-benzylalcohol (20 g) in dry CHCl3 (500 mL) was added MnO2 (160 g, 8 equivalents) and allowed to stir at room temperature for 12 h. The reaction mixture was filtered through celite and concentrated. The crude product was recrystallised from CHCl3/petrol ether to give N-acetyl-2-aminobenzaldehyde (14 g, 73%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07312358B2 |
| 出典データセット | uspto-grants-2007_12 |
| ORD ID | ord-6b72ab55819f44d887a00194ca641705 |
| 出典メモ | uspto-grants-2007_12 |