Benzene → HCID 21312565、化合物

HRID 971921ノート

反応式

HRID 971921 の反応式
[CH2:1]([C:3]1([CH2:12][CH3:13])[C:8](=[O:9])[NH:7][C:6](=[O:10])[NH:5][C:4]1=[O:11])[CH3:2].Cl[CH2:15][CH2:16][CH2:17][C:18]([O:20][CH3:21])=[O:19].[C:22](=[O:25])([O-])[O-:23].[K+].[K+].[CH:28]1[CH:33]=CC=C[CH:29]=1.[CH3:34]N(C)C=O>>[CH3:21][O:20][C:18]([CH2:17][CH2:16][CH2:15][N:7]1[C:8](=[O:9])[C:3]([CH2:1][CH3:2])([CH2:12][CH3:13])[C:4](=[O:11])[N:5]([CH2:29][CH2:28][CH2:33][C:22]([O:23][CH3:34])=[O:25])[C:6]1=[O:10])=[O:19]

参加物

6

反応物 5

HCID 241BenzeneHCID 2294BarbitalHCID 6228DimethylformamideHCID 11430Potassium CarbonateHCID 76612Butanoic acid, 4-chloro-, methyl ester

生成物 1

HCID 21312565HCID 21312565、化合物

実験手順

18.4 g (0.1 mol) of 5,5-diethylbarbituric acid are reacted with 28.7 g (0.21 mol) of methyl γ-chlorobutyrate according to Example 1. 15.2 g (0.11 mol) of potassium carbonate powder are used as the acid acceptor and 100 ml of benzene and 100 ml of dimethylformamide are used as the solvent. The reaction is carried out exactly according to Example 1 and likewise worked up. In this manner, 38.3 g (99.7% of theory) of a clear, slightly discoloured viscous product are obtained.

後処理

  1. customIn this manner, 38.3 g (99.7% of theory) of a clear, slightly discoloured viscous product are obtained

出典と根拠

ORDレコード
ord-38018ddc63f14eb8b330d469b9e561c9
出典データセット
uspto-grants-1979_07
特許番号
US04161603

反応ノート

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