Acetic Anhydride → HCID 21406318、化合物
反応式
[Br:1][C:2]1[C:3]([OH:17])=[C:4]([C:10]2[CH:11]=[CH:12][C:13](=[O:16])[NH:14][N:15]=2)[CH:5]=[C:6]([Br:9])[C:7]=1[CH3:8].[C:18](OC(=O)C)(=[O:20])[CH3:19]>C1C=CC=CC=1>[C:18]([O:17][C:3]1[C:2]([Br:1])=[C:7]([CH3:8])[C:6]([Br:9])=[CH:5][C:4]=1[C:10]1[CH:11]=[CH:12][C:13](=[O:16])[NH:14][N:15]=1)(=[O:20])[CH3:19]参加物
4
実験手順
A mixture of 1.0 g. of 6-(3,5-dibromo-2-hydroxy-4-methylphenyl)-3-(2H)pyridazinone and 2 ml. of acetic anhydride in 10 ml. of benzene was heated under reflux for 3 hours. After cooling, the so separated crystalline substance was recovered by filtration and dried to give 0.8 g. of the desired product as yellow needles of m.p. 220° C. (Yield 71.5%).
後処理
- additionA mixture of 1.0 g
- temperatureunder reflux for 3 hours
- temperatureAfter cooling
- filtrationthe so separated crystalline substance was recovered by filtration
- customdried
- customto give 0.8 g
出典と根拠
- ORDレコード
- ord-6b325ba319214b5088613f095aa73d09
- 出典データセット
- uspto-grants-1977_10
- 特許番号
- US04052395
反応ノート
読み込み中…