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2,3-Dihydro-1-methyl-1H-phosphole 1-oxide → 1-Methyl-1-oxophospholanyl dimethyl phosphine oxide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2,3-Dihydro-1-methyl-1H-phosphole 1-oxide | HCID 70104 | — |
| 反応物 | methylphosphonoylmethane | HCID 178503022 | — |
| 溶媒 | Dibutyl Phthalate | HCID 3026 | — |
| 生成物 | 1-Methyl-1-oxophospholanyl dimethyl phosphine oxide | HCID 21406646 | — |
反応手順
116 g of 1-methyl-1-oxophospholine and 6 g of tert.-butyl perpivalate in dibutyl phthalate are added dropwise with stirring under an oxygen-free atmosphere to 234 g of dimethyl phosphine oxide. The reaction temperature is 75° to 80° C. The starting materials are then distilled off. The residue consists of 185 g of 1-methyl-1-oxophospholanyl dimethyl phosphine oxide.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04052484 |
| 出典データセット | uspto-grants-1977_10 |
| ORD ID | ord-baa22e997a8a460bb171ee0725220b3f |
| 出典メモ | uspto-grants-1977_10 |