Acetic Anhydride → 3-Methoxycarbonyl-2-benzylidenepropanoic acid

HRID 972329ノート

反応式

HRID 972329 の反応式
[C:1]([CH2:4][C:5](=[CH:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)[C:6]([OH:8])=[O:7])([OH:3])=[O:2].[C:16](OC(=O)C)(=O)C>>[CH3:16][O:2][C:1]([CH2:4][C:5](=[CH:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)[C:6]([OH:8])=[O:7])=[O:3]

参加物

3

反応物 2

HCID 7918Acetic AnhydrideHCID 2229982-(Phenylmethylene)butanedioic acid

生成物 1

HCID 541581613-Methoxycarbonyl-2-benzylidenepropanoic acid

実験手順

2-Carboxymethyl-3-phenylpropenoic acid (4.1 g.) and acetic anhydride (9 ml.) are heated in the steam bath for 70 minutes. The mixture is concentrated to dryness and the residue triturated with ether, yield 3.6 g. This anhydride is dissolved in 7 ml. of methanol and heated in the steam bath for 1 hour.

後処理

  1. concentrationThe mixture is concentrated to dryness
  2. customthe residue triturated with ether, yield 3.6 g
  3. dissolutionThis anhydride is dissolved in 7 ml
  4. temperatureof methanol and heated in the steam bath for 1 hour

出典と根拠

ORDレコード
ord-557d6a4b762b40b5a1bb7e486c549e2b
出典データセット
uspto-grants-1977_10
特許番号
US04052511

反応ノート

読み込み中…