化工社化工社 化学情報印刷レポート · 研究参考用
Methyl Isocyanate → HCID 178485940、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methyl Isocyanate | HCID 12228 | — |
| 反応物 | HCID 178433288 | HCID 178433288 | — |
| 溶媒 | Acetonitrile | HCID 6342 | — |
| 生成物 | HCID 178485940 | HCID 178485940 | 58.8% |
反応手順
A mixture of 4-methyl-5-[(2-aminoethyl)thiomethyl]imidazole (5.1 g.) and methyl isocyanate (2.0 g.) in acetonitrile was heated for 18 hours in a pressure vessel at 100°. After cooling, the solid obtained was collected and recrystallised from isopropyl alcohol-acetonitrile to give N-methyl-N'-[2-((4-methyl-5-imidazolyl)methylthio)ethyl]urea (4.0 g.) m.p. 158°-159°.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04053473 |
| 出典データセット | uspto-grants-1977_10 |
| ORD ID | ord-9ca53a86750742b4af26748847283b7b |
| 出典メモ | uspto-grants-1977_10 |