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Hydrochloric Acid → N-methyl-N'-[2-((2-amino-4-imidazolyl)methylthio)ethyl]thiourea
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Cysteamine Hydrochloride | HCID 9082 | — |
| 反応物 | Methyl isothiocyanate | HCID 11167 | — |
| 反応物 | Picrate | HCID 4432340 | — |
| 反応物 | HCID 178479151 | HCID 178479151 | — |
| 反応物 | HCID 178511470 | HCID 178511470 | — |
| 生成物 | N-methyl-N'-[2-((2-amino-4-imidazolyl)methylthio)ethyl]thiourea | HCID 178486118 | — |
反応手順
Reaction of 2-amino-4-hydroxymethylimidazole hydrochloride (which is obtained by treating the picrate salt with hydrochloric acid) with cysteamine hydrochloride and reaction of the resulting 2-amino-4-[(2-aminoethyl)thiomethyl]imidazole with methyl isothiocyanate by the methods of Example 1 gives N-methyl-N'-[2-((2-amino-4-imidazolyl)methylthio)ethyl]thiourea.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04053473 |
| 出典データセット | uspto-grants-1977_10 |
| ORD ID | ord-21dffadcaddb4bf6ab8c9ec08927128e |
| 出典メモ | uspto-grants-1977_10 |