Ethanol → Benzene, 1,3-dichloro-5-nitro-

HRID 972667

反応式

HRID 972667 の反応式
[Cl:1][C:2]1[CH:8]=[C:7]([Cl:9])[C:5](N)=[C:4]([N+:10]([O-:12])=[O:11])[CH:3]=1.C(O)C.S(=O)(=O)(O)O.N([O-])=O.[Na+]>O>[Cl:1][C:2]1[CH:3]=[C:4]([N+:10]([O-:12])=[O:11])[CH:5]=[C:7]([Cl:9])[CH:8]=1

参加物

6

反応物 4

HCID 702EthanolHCID 1118Sulfuric AcidHCID 758932,4-Dichloro-6-nitroanilineHCID 23668193Sodium Nitrite

生成物 1

HCID 12064Benzene, 1,3-dichloro-5-nitro-収率 95%

試薬・触媒・溶媒 1

HCID 962Water溶媒2 回

実験手順

207 parts of 4,6-dichloro-2-nitro-aniline are introduced into 400 parts of ethanol and 900 parts of water, and 400 parts of concentrated sulfuric acid (98 percent strength by weight) are then added to the mixture. A solution of 105 parts of NaNO2 in 175 parts of water is run in at 80° C., as described in Example 1. The mixture is cooled and the product is filtered off. 182 parts (95% of theory) of 3,5-dichloro-nitro-benzene, of melting point 56°-59° C., are obtained.

後処理

  1. additionare then added to the mixture
  2. customis run in at 80° C.
  3. temperatureThe mixture is cooled
  4. filtrationthe product is filtered off

出典と根拠

ORDレコード
ord-c9bf08f38efb46f0987d460193911431
出典データセット
uspto-grants-1977_10
特許番号
US04053527

関連ノート

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