化工社化工社 化学情報印刷レポート · 研究参考用
Sulfuric Acid → 1-Chloro-3-nitrobenzene
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sulfuric Acid | HCID 1118 | — |
| 反応物 | Isopropanol | HCID 3776 | — |
| 反応物 | 2-Chloro-4-nitroaniline | HCID 8492 | — |
| 反応物 | Sodium Nitrite | HCID 23668193 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 1-Chloro-3-nitrobenzene | HCID 8489 | 90% |
反応手順
172.5 parts of 2-chloro-4-nitro-aniline are introduced into 180 parts of isopropanol and 300 parts of water, and 200 parts of concentrated sulfuric acid (98 percent strength by weight) are then added to the mixture. A solution of 125 parts of NaNO2 in 175 parts of water is run in at 50° C., as described in Example 1. The mixture is cooled, 400 parts of water are added and the product is filtered off. 142 parts (90% of theory) of 3-chloro-nitro-benzene, of melting point 40°-42° C., are obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04053527 |
| 出典データセット | uspto-grants-1977_10 |
| ORD ID | ord-bb2327d0a7014402a0420096593a1132 |
| 出典メモ | uspto-grants-1977_10 |