Ethyl 5-(2-propyl-5-thiazolyl)2,4-pentadienoate → 2-Propyl-5-thiazole-pentanoic acid

HRID 972838ノート

反応式

HRID 972838 の反応式
[CH2:1]([C:4]1[S:5][C:6]([CH:9]=[CH:10][CH:11]=[CH:12][C:13]([O:15]CC)=[O:14])=[CH:7][N:8]=1)[CH2:2][CH3:3].[H][H]>>[CH2:1]([C:4]1[S:5][C:6]([CH2:9][CH2:10][CH2:11][CH2:12][C:13]([OH:15])=[O:14])=[CH:7][N:8]=1)[CH2:2][CH3:3]

参加物

3

反応物 2

HCID 54337588Ethyl 5-(2-propyl-5-thiazolyl)2,4-pentadienoateHCID 178418361HCID 178418361、化合物

生成物 1

HCID 214055872-Propyl-5-thiazole-pentanoic acid

実験手順

Using the procedure of Example 10, ethyl 5-(2-propyl-5-thiazolyl)2,4-pentadienoate was reacted with hydrogen in the presence of activated carbon containing 10% palladium and the resulting product was saponified to obtain 2-propyl-5-thiazole-pentanoic acid. The latter product was reacted with α,β-ethanedisulfonic acid to obtain the hemi-α,β-ethane disulfonate of 2-propyl-5-thiazole-pentanoic acid melting at 124°C.

出典と根拠

ORDレコード
ord-e0ef3ecf46ab47c5815f51e44188846c
出典データセット
uspto-grants-1977_10
特許番号
US04053618

反応ノート

読み込み中…