4-[4-(4-Fluorophenyl)methylphenyl]piperidine → 2-Benzyl-1-[4-(4-(4-(4-fluorophenyl)methylphenyl)piperidin-1-yl)butyrylamino]benzene

HRID 973

反応式

HRID 973 の反応式
[CH2:1]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[NH:14][C:15](=[O:20])[CH2:16][CH2:17][CH2:18]Br)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[F:21][C:22]1[CH:27]=[CH:26][C:25]([CH2:28][C:29]2[CH:34]=[CH:33][C:32]([CH:35]3[CH2:40][CH2:39][NH:38][CH2:37][CH2:36]3)=[CH:31][CH:30]=2)=[CH:24][CH:23]=1>>[CH2:1]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[NH:14][C:15](=[O:20])[CH2:16][CH2:17][CH2:18][N:38]1[CH2:39][CH2:40][CH:35]([C:32]2[CH:33]=[CH:34][C:29]([CH2:28][C:25]3[CH:24]=[CH:23][C:22]([F:21])=[CH:27][CH:26]=3)=[CH:30][CH:31]=2)[CH2:36][CH2:37]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

参加物

3

反応物 2

HCID 154621204-[4-(4-Fluorophenyl)methylphenyl]piperidineHCID 196942302-Benzyl-1-(4-bromobutyrylamino)benzene

生成物 1

HCID 196942362-Benzyl-1-[4-(4-(4-(4-fluorophenyl)methylphenyl)piperidin-1-yl)butyrylamino]benzene

実験手順

The compound (11) synthesized in Reference Example 11 and the compound (7) synthesized in Reference Example 7 were used to produce the above compound in the same way as Example 1.

後処理

  1. customto produce the above compound in the same way as Example 1

出典と根拠

ORDレコード
ord-71e7f2ae1b1b4d3b94456563cef0ba78
出典データセット
uspto-grants-1998_03
特許番号
US05723475

関連ノート

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