関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Trifluoroacetic acid | HCID 6422 | — |
| 反応物 | Tetrafluoroborate | HCID 26255 | — |
| 反応物 | Ethyl 5-amino-6-ethyl-3,4-dihydro-4-oxothieno[2,3-d]PYRIMIDINE-2-CARBOXYLATE | HCID 12516925 | — |
| 反応物 | Potassium trifluoroacetate | HCID 23662811 | — |
| 生成物 | Ethyl 6-ethyl-3,4-dihydro-5-hydroxy-4-oxothieno[2,3-d]PYRIMIDINE-2-CARBOXYLATE | HCID 23330393 | — |
反応手順
The diazonium fluoroborate salt is prepared as in Procedure 63 from the amino compound produced in Procedure 51 yielding 0.03 mole of the required idazonium fluoborate. The latter is added in one portion to a solution of 0.03 mole of potassium trifluoroacetate in 13 ml. of trifluoroacetic acid at 0° C. The mixture is stirred at 25° C. for 1 hour and then refluxed overnight. The trifluoroacetic acid is evaporated in vacuo to give a residue which is triturated with water and filtered to give the desired product.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04054656 |
|---|
| 出典データセット | uspto-grants-1977_10 |
|---|
| ORD ID | ord-2d90e88b0aae47a48537ed6a9b4507da |
|---|
| 出典メモ | uspto-grants-1977_10 |
|---|
