Methane → 2-(2,6-Dichloro-4-trifluoromethylphenylhydrazono)propanal 1-oxime

HRID 973675

反応式

HRID 973675 の反応式
[Cl:1][C:2]1[CH:7]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:5]=[C:4]([Cl:12])[C:3]=1[NH:13][NH2:14].O=[C:16]([CH3:20])[CH:17]=[N:18][OH:19].S([O-])([O-])(=O)=O.[Mg+2].C>CCOCC>[Cl:1][C:2]1[CH:7]=[C:6]([C:8]([F:9])([F:11])[F:10])[CH:5]=[C:4]([Cl:12])[C:3]=1[NH:13][N:14]=[C:16]([CH3:20])[CH:17]=[N:18][OH:19]

参加物

6

反応物 4

HCID 297MethaneHCID 24083Sulfuric acid magnesium salt (1:1)HCID 688223[2,6-Dichloro-4-(trifluoromethyl)phenyl]hydrazineHCID 63992132-Oxopropanal-1-oxime

生成物 1

HCID 1363412052-(2,6-Dichloro-4-trifluoromethylphenylhydrazono)propanal 1-oxime

試薬・触媒・溶媒 1

HCID 3283Diethyl Ether溶媒2 回

実験手順

A solution of 2,6-dichloro-4-trifluoromethylphenylhydrazine (10.2 g) in ether (15 ml) was added with cooling to a solution of `2-oxopropanal 1-oxime (3.62 g) in ether (15 ml) at 0°. The mixture was stirred at room temperature overnight and magnesium sulphate and charcoal added. The mixture was filtered and solvent evaporated under reduced pressure. The residue was purified by column chromatography to give 2-(2,6-dichloro-4-trifluoromethylphenylhydrazono)propanal 1-oxime, m.p, c.108°.

後処理

  1. filtrationThe mixture was filtered
  2. customsolvent evaporated under reduced pressure
  3. customThe residue was purified by column chromatography

出典と根拠

ORDレコード
ord-f5e3e5b3d37946958d7541f859f44bf7
出典データセット
uspto-grants-1991_11
特許番号
US05064844

関連ノート

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