Carbon tetrabromide → 2-(2,6-dichloro-4-trifluoromethylphenyl)-4-(2,2-dibromo-vinyl)-2H-1,2,3-triazole

HRID 973681ノート

反応式

HRID 973681 の反応式
[Cl:1][C:2]1[CH:7]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:5]=[C:4]([Cl:12])[C:3]=1[N:13]1[N:17]=[C:16]([CH:18]=O)[CH:15]=[N:14]1.[Br-].[Br-].C1([PH+](C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.C1([PH+](C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.[C:60](Br)(Br)([Br:62])[Br:61].C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1>ClCCl.CCCCCC>[Cl:1][C:2]1[CH:7]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:5]=[C:4]([Cl:12])[C:3]=1[N:13]1[N:17]=[C:16]([CH:18]=[C:60]([Br:62])[Br:61])[CH:15]=[N:14]1

参加物

7

反応物 4

HCID 11205Carbon tetrabromideHCID 11776TriphenylphosphineHCID 197783082-(2,6-Dichloro-4-trifluoromethylphenyl)-1,2,3-triazole-4-carboxaldehydeHCID 22664940Bis(triphenylphosphanium) dibromide

生成物 1

HCID 199888802-(2,6-dichloro-4-trifluoromethylphenyl)-4-(2,2-dibromo-vinyl)-2H-1,2,3-triazole

試薬・触媒・溶媒 2

HCID 6344Dichloromethane溶媒3 回HCID 8058Hexane溶媒

実験手順

A solution of 2-(2,6-dichloro-4-trifluoromethylphenyl)-2H-1,2,3-triazole-4-carboxaldehyde (3.1 g), in dichloromethane (20 ml) was added to a solution of triphenylphosphonium dibromide at -20° (prepared by mixing a solution of carbon tetrabromide (31.2 g) in dichloromethane (30 ml) with a solution of triphenylphosphine (21 g) in dichloromethane (70 ml)) and the mixture stirred for 1 hour. Hexane was added and the mixture filtered. The filtrate was worked up to give 2-(2,6-dichloro-4-trifluoromethylphenyl)-4-(2,2-dibromo-vinyl)-2H-1,2,3-triazole. 89°-91° . (Compound 24)

後処理

  1. customprepared
  2. filtrationthe mixture filtered

出典と根拠

ORDレコード
ord-a02c221db50546a9a16e940ad6094e16
出典データセット
uspto-grants-1991_11
特許番号
US05064844

反応ノート

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