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Acetic Acid → 5-[4-(4-Oxo-1,4-dihydropyridin-1-yl)phenyl]-6-methyl-3H,6H-1,3,4-thiadiazin-2-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acetic Acid | HCID 176 | — |
| 反応物 | 4H-pyran-4-one | HCID 7968 | — |
| 反応物 | 5-(4-aminophenyl)-6-methyl-3H,6H-1,3,4-thiadiazine-2-one | HCID 22498613 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 5-[4-(4-Oxo-1,4-dihydropyridin-1-yl)phenyl]-6-methyl-3H,6H-1,3,4-thiadiazin-2-one | HCID 19794222 | — |
反応手順
A stirred mixture of 5-(4-aminophenyl)-6-methyl-3H,6H -1,3,4-thiadiazine-2-one (0.54 g). 4H-pyran-4-one (0.26 g), glacial acetic acid (0.15 g) and water (20 ml) was heated under reflux for 24 hours to give a solid. 0.54 g. Recrystallisation from aqueous ethanol gave the title compound, 0.28 g, which darkened at 265° C. and sublimed at 273-275° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05066653 |
| 出典データセット | uspto-grants-1991_11 |
| ORD ID | ord-aff74887215d45388a8541de1e6858e6 |
| 出典メモ | uspto-grants-1991_11 |