化工社化工社 化学情報印刷レポート · 研究参考用
Benzaldehyde → N-Benzylidene-2,4-difluorobenzylamine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzaldehyde | HCID 240 | — |
| 反応物 | Water | HCID 962 | — |
| 反応物 | 2,4-Difluorobenzylamine | HCID 2733244 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | N-Benzylidene-2,4-difluorobenzylamine | HCID 19986446 | — |
反応手順
50.2 g (0.35 mol) of 2,4-difluorobenzylamine and 37.1 g (0.35 mol) of benzaldehyde are dissolved in 140 ml of toluene and heated to reflux. The water produced is separated off using a water separator. The reaction is complete (GC check) after two hours. The solution is evaporated on a vacuum rotary evaporator. 78.9 g (97% of theory) of a slightly yellow liquid are obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05068371 |
| 出典データセット | uspto-grants-1991_11 |
| ORD ID | ord-6267607942ce40488e1d03f6daa5f76d |
| 出典メモ | uspto-grants-1991_11 |