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Cyclohexane → 3-Trifluoromethyl-2-(2-aminophenylthio)benzonitrile
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Cyclohexane | HCID 8078 | — |
| 反応物 | 2-Aminothiophenol | HCID 8713 | — |
| 反応物 | 2-Fluoro-3-(trifluoromethyl)benzonitrile | HCID 518974 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | 3-Trifluoromethyl-2-(2-aminophenylthio)benzonitrile | HCID 19969445 | — |
反応手順
Using a procedure analagous to that of Example 3(a), 2-aminothiophenol (6.26 g, 50 mmol) was combined with 3-trifluoromethyl-2-fluorobenzonitrile (1 eq) in DMF solvent (50 ml) to give the title compound as a white solid from cyclohexane (10.41 g).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05607929 |
| 出典データセット | uspto-grants-1997_03 |
| ORD ID | ord-5ea13c82a1fe4e9fb68e4b02a5c661d9 |
| 出典メモ | uspto-grants-1997_03 |