HCID 15070022、化合物 → 2-Methyl-4-oxa-2,8-diazabicyclo[4.3.0]nonane
反応式
[CH3:1][N:2]1[CH2:10][O:9][CH2:8][CH:7]2[CH:3]1[CH2:4][N:5](C(OCC)=O)[CH2:6]2>O>[CH3:1][N:2]1[CH2:10][O:9][CH2:8][CH:7]2[CH:3]1[CH2:4][NH:5][CH2:6]2参加物
3
実験手順
9 g (42 mmol) of ethyl 2-methyl-4-oxa-2,8-diazabicyclo[4.3.0]nonane-8-carboxylate are heated under reflux with 28 g of Ba(OH)2 ·8H2O in 280 ml of water overnight. The BaCO3 is filtered off with suction, the filtrate is concentrated and the residue is boiled up with dioxane. The dioxane solution is concentrated and the residue is distilled.
後処理
- filtrationThe BaCO3 is filtered off with suction
- concentrationthe filtrate is concentrated
- concentrationThe dioxane solution is concentrated
- distillationthe residue is distilled
出典と根拠
- ORDレコード
- ord-3aaff2ae6d324ef9b1c15dbaf73e17a2
- 出典データセット
- uspto-grants-1997_03
- 特許番号
- US05607942
反応ノート
読み込み中…