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Hydrochloric Acid → 1-(3-Furyl)-1-(4-methyl-5-oxazolyl)ethene
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Diethyl Ether | HCID 3283 | — |
| 反応物 | Sodium Bicarbonate | HCID 516892 | — |
| 反応物 | 1-(3-Furyl)-1-(4-methyl-5-oxazolyl)ethanol | HCID 9794153 | — |
| 溶媒 | Chloroform | HCID 6212 | — |
| 生成物 | 1-(3-Furyl)-1-(4-methyl-5-oxazolyl)ethene | HCID 18936291 | — |
反応手順
1-(3-Furyl)-1-(4-methyl-5-oxazolyl)ethanol (900 mg) in dry chloroform was treated with 1M anhydrous hydrogen chloride in diethylether (1.1 equivalents). After 10 minutes at room temperature, aqueous sodium hydrogen carbonate was added and the mixture was extracted with dichloromethane. The material thus obtained was purified by flash chromatography to give the title compound as an almost colourless liquid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05607956 |
| 出典データセット | uspto-grants-1997_03 |
| ORD ID | ord-21c6a0acc52841ffa5708d6978258dba |
| 出典メモ | uspto-grants-1997_03 |