Hydrochloric Acid → HCID 19972019、化合物
反応式
[ClH:1].C(OC([NH:9][CH:10]([P:18]([CH:23]([NH:31]C(OC(C)(C)C)=O)[CH2:24][C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1)(=[O:22])[O:19][CH2:20][CH3:21])[CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)=O)(C)(C)C>CO>[ClH:1].[NH2:31][CH:23]([P:18]([CH:10]([NH2:9])[CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)(=[O:22])[O:19][CH2:20][CH3:21])[CH2:24][C:25]1[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=1参加物
4
実験手順
An about 3N methanolic hydrochloric acid (10 ml) is added at room temperature with stirring to a solution of the bisalkylated phosphinic acid ester 10 (103 mg, 0.19 mol) in methanol (5 ml). After 3 hours, the reaction solution is concentrated under reduced pressure. The phosphinic acid ester hydrochloride 15 (69 mg, 97% of theory) is obtained.
後処理
- concentration