関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 1,2,4,5-Tetrachlorobenzene | HCID 7270 | — |
| 反応物 | Lithium Chloride | HCID 433294 | — |
| 反応物 | Sodium borohydride | HCID 4311764 | — |
| 触媒 | Bis(cyclopentadienyl)titanium(IV) chloride | HCID 416358 | — |
| 生成物 | 1,2,3-Trichlorobenzene | HCID 6895 | — |
反応手順
A flask equipped with a magnetic stir bar and a water cooled condenser with an oil bubbler was charged with 1,2,4,5-tetrachlorobenzene (648 mg, 3.0 mmol), sodium tetrahydridoborate (1135 mg, 30.0 mmol), bis(η5 -cyclopentadienyl)titanium dichloride (75 mg, 0.3 mmol) and 1-methyl-2pyrrolidine (NMP; 30.0 ml). The reaction mixture was heated at 96° C. in an oil bath. After 4.25 hours, lithium chloride (1.09 g, 30.0 mmol) was added. Aliquots were withdrawn by syringe, quenched with water, and extracted with diethyl ether. The ether layer was analyzed with the results shown in the following table. Only trichlorobenzene was produced.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 特許番号 | US05608135 |
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| 出典データセット | uspto-grants-1997_03 |
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| ORD ID | ord-afb72519c4d7429caf96dfaa4c7ee144 |
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| 出典メモ | uspto-grants-1997_03 |
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