8-Azido-1-octanol → 8-Amino-1-octanol
反応式
[N:1]([CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][OH:12])=[N+]=[N-]>C(O)C.[Pd].CC([O-])=O.CC([O-])=O.[Pb+2]>[NH2:1][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][OH:12]参加物
4
実験手順
8-Azido-octan-1-ol (1.99 g, 11.6 mmol) was dissolved in ethanol (25 mL) and Lindlar catalyst (200 mg) was added. The solution was hydrogenated at 50 psi, 30° C. for 2 hours. The catalyst was removed by filtration through Kieselguhr and the solvent was removed in vacuo to give a white solid 1.33 g (79% yield), mp 48°-53° C.;
後処理
- customThe catalyst was removed by filtration through Kieselguhr
- customthe solvent was removed in vacuo
出典と根拠
- ORDレコード
- ord-fd8c1ef75d4b4d6ba5b5d39f72ac4ac1
- 出典データセット
- uspto-grants-1997_03
- 特許番号
- US05610145
反応ノート
読み込み中…