1-[4-[(4-Fluorophenyl)methyl]phenyl]piperazine → 2-Benzyl-1-[6-(4-(4-(4-fluorophenyl)methylphenyl)piperazin-1-yl)hexanoylamino]benzene

HRID 976

反応式

HRID 976 の反応式
[CH2:1]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[NH:14][C:15](=[O:22])[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20]Br)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[F:23][C:24]1[CH:29]=[CH:28][C:27]([CH2:30][C:31]2[CH:36]=[CH:35][C:34]([N:37]3[CH2:42][CH2:41][NH:40][CH2:39][CH2:38]3)=[CH:33][CH:32]=2)=[CH:26][CH:25]=1>>[CH2:1]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[NH:14][C:15](=[O:22])[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][N:40]1[CH2:39][CH2:38][N:37]([C:34]2[CH:33]=[CH:32][C:31]([CH2:30][C:27]3[CH:28]=[CH:29][C:24]([F:23])=[CH:25][CH:26]=3)=[CH:36][CH:35]=2)[CH2:42][CH2:41]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

参加物

3

反応物 2

HCID 15199981-[4-[(4-Fluorophenyl)methyl]phenyl]piperazineHCID 196942342-Benzyl-1-(6-bromohexanoylamino)benzene

生成物 1

HCID 196942392-Benzyl-1-[6-(4-(4-(4-fluorophenyl)methylphenyl)piperazin-1-yl)hexanoylamino]benzene

実験手順

The compound (12) synthesized in Reference Example 12 and the compound (5) synthesized in Reference Example 5 were used to produce the above compound in the same way as Example 1.

後処理

  1. customto produce the above compound in the same way as Example 1

出典と根拠

ORDレコード
ord-4e9e448f686b4d538c557bf57797f3cf
出典データセット
uspto-grants-1998_03
特許番号
US05723475

関連ノート

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