Hydrochloric Acid → HCID 178501833、化合物

HRID 976257ノート

反応式

HRID 976257 の反応式
[ClH:1].[NH2:2][C@H:3]1[CH2:8][CH2:7][C@H:6]([O:9][CH2:10][C:11]([O:13][C:14](C)(C)C)=[O:12])[CH2:5][CH2:4]1>CO>[ClH:1].[NH2:2][C@H:3]1[CH2:8][CH2:7][C@H:6]([O:9][CH2:10][C:11]([O:13][CH3:14])=[O:12])[CH2:5][CH2:4]1

参加物

4

反応物 2

HCID 313Hydrochloric AcidHCID 178451370HCID 178451370、化合物

生成物 1

HCID 178501833HCID 178501833、化合物

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

Hydrochloric acid gas is piped for an hour over a solution of 59.4 g of tert.butyl (trans-4-aminocyclohexyl)oxyacetate in 500 ml of methanol, cooled in an ice bath, and then the mixture is stirred overnight at ambient temperature. It is evaporated to dryness, the residue is triturated with acetone and the solid is suction filtered and dried.

後処理

  1. temperaturecooled in an ice bath
  2. customIt is evaporated to dryness
  3. customthe residue is triturated with acetone
  4. filtrationfiltered
  5. customdried

出典と根拠

ORDレコード
ord-78f9cc1f0fb44aff9dfe05c9f3b79710
出典データセット
uspto-grants-1997_03
特許番号
US05612335

反応ノート

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