2-Amino-N-methoxybenzamide → Diethyl(3-methoxy-4-{[4-{[2-(methoxycarbamoyl)phenyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}benzyl)phosphonate

反応式

[Cl:1][c:2]1[n:3][c:4]([NH:12][c:13]2[c:14]([O:28][CH3:29])[cH:15][c:16]([CH2:17][P:18]([O:19][CH2:20][CH3:21])([O:22][CH2:23][CH3:24])=[O:25])[cH:26][cH:27]2)[n:5][cH:6][c:7]1[C:8]([F:9])([F:10])[F:11].[NH2:30][c:31]1[c:32]([C:33](=[O:34])[NH:35][O:36][CH3:37])[cH:38][cH:39][cH:40][cH:41]1>>[c:2]1([NH:30][c:31]2[c:32]([C:33](=[O:34])[NH:35][O:36][CH3:37])[cH:38][cH:39][cH:40][cH:41]2)[n:3][c:4]([NH:12][c:13]2[c:14]([O:28][CH3:29])[cH:15][c:16]([CH2:17][P:18]([O:19][CH2:20][CH3:21])([O:22][CH2:23][CH3:24])=[O:25])[cH:26][cH:27]2)[n:5][cH:6][c:7]1[C:8]([F:9])([F:10])[F:11]

参加物

反応物 2

HCID 123927072-Amino-N-methoxybenzamide

HCID 86654002Diethyl (4-{[4-chloro-5-(trifluoromethyl) pyrimidin-2-yl]amino}-3-methoxybenzyl)phosphonate

生成物 1

HCID 58292946Diethyl(3-methoxy-4-{[4-{[2-(methoxycarbamoyl)phenyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}benzyl)phosphonate

出典と根拠

ORDレコード: ord-31f037bb559d4b77a9c3edb88d6e227a
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…