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3-(4-Tert-butoxycarbonylaminomethylphenyl)-2-oxo-5-oxazolidinecarboxylic acid → Benzyl 3-{1-[3-(4-tert-butoxycarbonylaminomethylphenyl)-2-oxo-5-oxazolidinylcarbonyl]-4-piperazinyl}propionate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-(4-Tert-butoxycarbonylaminomethylphenyl)-2-oxo-5-oxazolidinecarboxylic acid | HCID 19965556 | — |
| 反応物 | Benzyl 3-(1-piperazinyl)propionate | HCID 54224547 | — |
| 生成物 | Benzyl 3-{1-[3-(4-tert-butoxycarbonylaminomethylphenyl)-2-oxo-5-oxazolidinylcarbonyl]-4-piperazinyl}propionate | HCID 19965564 | — |
反応手順
In analogy to Example 4, reaction of benzyl 3-(1-piperazinyl)propionate and 3-(4-tert-butoxycarbonylaminomethylphenyl)-2-oxo-5-oxazolidinecarboxylic acid gives benzyl 3-{1-[3-(4-tert-butoxycarbonylaminomethylphenyl)-2-oxo-5-oxazolidinylcarbonyl]-4-piperazinyl}propionate, m.p. 128°-130°.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05614535 |
| 出典データセット | uspto-grants-1997_03 |
| ORD ID | ord-ee23afdfc77f4115abecdf4da23076cb |
| 出典メモ | uspto-grants-1997_03 |