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Acetate → 3-{1-[3-(4-Aminomethylphenyl)-2-oxo-5-oxazolidinylcarbonyl]-4-piperazinyl}propionic acid, dihydrochloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acetate | HCID 175 | — |
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | 3-{1-[3-(4-Tert-butoxycarbonylaminomethylphenyl)-2-oxo-5-oxazolidinylcarbonyl]-4-piperazinyl}propionic acid | HCID 19965488 | — |
| 生成物 | 3-{1-[3-(4-Aminomethylphenyl)-2-oxo-5-oxazolidinylcarbonyl]-4-piperazinyl}propionic acid, dihydrochloride | HCID 131719940 | — |
反応手順
0.43 g of 3-{1-[3-(4-tert-butoxycarbonylaminomethylphenyl)-2-oxo-5-oxazolidinylcarbonyl]-4-piperazinyl}propionic acid, acetate, is stirred in 30 ml of ethereal HCl solution at room temperature. The precipitate formed is filtered off with suction, washed with a little ether and dried. 3-{1-[3-(4-aminomethylphenyl)-2-oxo-5-oxazolidinylcarbonyl]-4-piperazinyl}propionic acid, dihydrochloride, is obtained, m.p. 184°-186°.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05614535 |
| 出典データセット | uspto-grants-1997_03 |
| ORD ID | ord-d90db408527948a6b84d131e63b4a8f9 |
| 出典メモ | uspto-grants-1997_03 |