Hydrochloric Acid → HCID 178447643、化合物
反応式
Cl.[CH3:2][N:3]1[C:7]([CH:8]([CH3:15])[CH2:9][CH2:10][C:11]([O:13]C)=[S:12])=[N:6][N:5]=[N:4]1>O>[CH3:2][N:3]1[C:7]([CH:8]([CH3:15])[CH2:9][CH2:10][C:11]([OH:13])=[S:12])=[N:6][N:5]=[N:4]1参加物
4
実験手順
20% aqueous Hydrochloric acid (150 ml) is added to methyl 4-(1-methyl-1,2,3,4-tetrazol-5-yl)thiovalerate (17 g) and the mixture is refluxed for 2 hours. After cooling, the reaction mixture is diluted with water and extracted with chloroform. The chlorofom solution is washed with aqueous saturated sodium chloride solution and dried over magnesium sulfate. Chloroform is distilled off to give 4-(1-methyl-1,2,3,4-tetrazol-5-yl)thio-valeric acid, colorless liquid, nD26 =1.5133.
後処理
- temperaturethe mixture is refluxed for 2 hours
- temperatureAfter cooling
- extractionextracted with chloroform
- washThe chlorofom solution is washed with aqueous saturated sodium chloride solution
- dry with materialdried over magnesium sulfate
- distillationChloroform is distilled off
出典と根拠
- ORDレコード
- ord-66a854a61ef94e1db8cb2e85e07aefe9
- 出典データセット
- uspto-grants-1987_05
- 特許番号
- US04663323
反応ノート
読み込み中…