Benzimidazole → 4-[2-(1H-Benzimidazol-1-yl)ethoxy]phenol

反応式

C([O:8][C:9]1[CH:14]=[CH:13][C:12]([O:15][CH2:16][CH2:17]Br)=[CH:11][CH:10]=1)C1C=CC=CC=1.[N:19]1[C:23]2[CH:24]=[CH:25][CH:26]=[CH:27][C:22]=2[NH:21][CH:20]=1>>[N:19]1([CH2:17][CH2:16][O:15][C:12]2[CH:11]=[CH:10][C:9]([OH:8])=[CH:14][CH:13]=2)[C:23]2[CH:24]=[CH:25][CH:26]=[CH:27][C:22]=2[N:21]=[CH:20]1

参加物

反応物 2

HCID 5798Benzimidazole

HCID 107570881-(Benzyloxy)-4-(2-bromoethoxy)benzene

生成物 1

HCID 202052654-[2-(1H-Benzimidazol-1-yl)ethoxy]phenol

実験手順

In a manner analogous to that described in Example 1(b), from 1-benzyloxy-4-(2-bromoethoxy)benzene and benzimidazole, 4-[2-(1-benzimidazolyl)ethoxy]phenol was obtained.

出典と根拠

ORDレコード: ord-52465b84c6fa4a3a83e9369aa31ae7ba
出典データセット: uspto-grants-1987_05
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04663462

反応ノート

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