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3,4-Dichloroaniline → 5-Chloro-3-(3,4-dichlorophenyl)-4-thiazolidinone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3,4-Dichloroaniline | HCID 7257 | — |
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 反応物 | 3-(3,4-Dichlorophenyl)-1,3-thiazolidin-4-one | HCID 4585437 | — |
| 反応物 | Thiazolidinone | HCID 20553328 | — |
| 生成物 | 5-Chloro-3-(3,4-dichlorophenyl)-4-thiazolidinone | HCID 13853453 | — |
反応手順
3,4-Dichloroaniline was converted to 3-(3,4-dichlorophenyl)-4-thiazolidinone as outlined in Example 1. This thiazolidinone, which had a melting point of 145°-146° C., was chlorinated with thionyl chloride to form 5-chloro-3-(3,4-dichlorophenyl)-4-thiazolidinone having a melting point of 100°-103° C. Recrystallization of this product from ethanol gave 3-(3,4-dichlorophenyl)-5-ethoxy-4-thiazolidinone which had a melting point of 61°-65° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04664694 |
| 出典データセット | uspto-grants-1987_05 |
| ORD ID | ord-beee820f7b0c4a32aec5ec4e80c04404 |
| 出典メモ | uspto-grants-1987_05 |