Ammonia → 5-(Chloromethyl)-2-phenyl-1,3-oxazolidine
反応式
[CH:1](=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:9]([CH:11]1O[CH2:12]1)[Cl:10].[NH3:14]>>[C:2]1([CH:1]2[NH:14][CH2:12][CH:11]([CH2:9][Cl:10])[O:8]2)[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1参加物
4
実験手順
According to Carter and Blattacharye [J. Amer. Chem. Soc 75, 2503 (1953)], D,L-carnitine is obtained by reacting benzaldehyde, epichlorohydrin and ammonia in an organic solvent, the reaction product 2-phenyl-5-chloromethyloxazolidine is isolated and said compound is subsequently transformed into D,L-carnitine according to known techniques, with a yield of 20-25%.
出典と根拠
- ORDレコード
- ord-7005e47fe6954e10b169843c7524f5f6
- 出典データセット
- uspto-grants-1987_05
- 特許番号
- US04664852
反応ノート
読み込み中…