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HRID 978627作成日:2026年10月26日

Folic Acid → Tetrahydrofolic acid

https://huagongshe.com/reaction/978627

反応式

関与物質

役割名称HCID仕込み量
反応物Folic AcidHCID 135398658—
触媒Platinum oxide (PtO)HCID 82844—
溶媒WaterHCID 962—
生成物Tetrahydrofolic acidHCID 13544474274.9%

反応手順

Then, a suspension of 0.0687 g of platinum oxide (containing the noble metal in an amount of 1.5% by weight based on the folic acid) in 50 ml of distilled water was added to the flask, and hydrogenation was carried out in the same manner as described in Example 1 to obtain 2.973 g (74.9% yield) of tetrahydrofolic acid.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US04665176
出典データセットuspto-grants-1987_05
ORD IDord-357e9547bcf64640be111d58f575916c
出典メモuspto-grants-1987_05