化工社化工社 化学情報印刷レポート · 研究参考用
Folic Acid → Tetrahydrofolic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Folic Acid | HCID 135398658 | — |
| 触媒 | Rhodium | HCID 23948 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | Tetrahydrofolic acid | HCID 135444742 | 75.3% |
反応手順
Then, a suspension of 0.230 g of a 5% rhodium-activated carbon catalyst (containing the noble metal in an amount of 0.55% by weight based on the folic acid) in 25 ml of distilled water was added to the flask, and hydrogenation was carried out in the same manner as described in Example 1 to obtain 1.593 g (75.3% yield) of tetrahydrofolic acid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04665176 |
| 出典データセット | uspto-grants-1987_05 |
| ORD ID | ord-19ae6309e767423783f3b83e5864aec1 |
| 出典メモ | uspto-grants-1987_05 |