3-Methoxypropylamine → 2-chloro-5-methylamino-4-nitro-N-gamma-methoxypropylaniline
反応式
[Cl:1][C:2]1[C:9](Cl)=[CH:8][C:5]([NH:6][CH3:7])=[C:4]([N+:11]([O-:13])=[O:12])[CH:3]=1.[CH3:14][O:15][CH2:16][CH2:17][CH2:18][NH2:19]>>[Cl:1][C:2]1[CH:3]=[C:4]([N+:11]([O-:13])=[O:12])[C:5]([NH:6][CH3:7])=[CH:8][C:9]=1[NH:19][CH2:18][CH2:17][CH2:16][O:15][CH3:14]参加物
3
実験手順
0.059 mole (13 g) of 4,5-dichloro-2-nitro-N-methylaniline prepared in the previous stage is heated for 4 hours in 40 ml of 3-methoxypropylamine on a steam bath. After dilution with iced water and acidifying with concentrated hydrochloric acid, the expected product is filtered off. Recrystallized from 96° ethanol, it melts at 99° C.
後処理
- filtrationAfter dilution with iced water and acidifying with concentrated hydrochloric acid, the expected product is filtered off
- customRecrystallized from 96° ethanol, it melts at 99° C.
出典と根拠
- ORDレコード
- ord-a1bced3aac7848849ba5ddfb4ac4b4cf
- 出典データセット
- uspto-grants-1987_05
- 特許番号
- US04666453
反応ノート
読み込み中…