1,3-dimethyl-4-nitro-1H-pyrazole-5-carbonitrile → 4-Amino-1,3-dimethyl-1H-pyrazole-5-carbonitrile

HRID 979053

反応式

HRID 979053 の反応式
[CH3:1][N:2]1[C:6]([C:7]#[N:8])=[C:5]([N+:9]([O-])=O)[C:4]([CH3:12])=[N:3]1>CO.[Ni]>[CH3:1][N:2]1[C:6]([C:7]#[N:8])=[C:5]([NH2:9])[C:4]([CH3:12])=[N:3]1

参加物

4

反応物 1

HCID 965071,3-dimethyl-4-nitro-1H-pyrazole-5-carbonitrile

生成物 1

HCID 123358164-Amino-1,3-dimethyl-1H-pyrazole-5-carbonitrile

試薬・触媒・溶媒 2

HCID 935Nickel触媒HCID 887Methanol溶媒

実験手順

Two-hundred and seventy-two g of 1,3-dimethyl-4-nitro-5-cyano-pyrazole was subjected to catalytic hydrogenation in methanol using a Raney nickel catalyst. The catalyst was filtered away and the filtrate concentrated. The product solidified, mp 109°-111° C.

後処理

  1. filtrationThe catalyst was filtered away
  2. concentrationthe filtrate concentrated

出典と根拠

ORDレコード
ord-80572243f85a460c9c65208bd90fc4a8
出典データセット
uspto-grants-1987_05
特許番号
US04666908

関連ノート

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