化工社化工社 化学情報印刷レポート · 研究参考用
Sodium Dithionite → 4-chloro-3-hydroxy-10H-phenothiazine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sodium Dithionite | HCID 24489 | — |
| 反応物 | 3H-Phenothiazin-3-one, 4-chloro- | HCID 11776748 | — |
| 溶媒 | Water | HCID 962 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | 4-chloro-3-hydroxy-10H-phenothiazine | HCID 9881418 | 95% |
反応手順
A solution of Na2S2O4 (70 g) in water (500 ml) was added to a solution of 4-chloro-3H-phenothiazin-3-one (50 g) in DMF (1200 ml). The reaction mixture was stirred at room temperature for 3 hours and then poured in 5 liters of water. The resulting precipitate was then filtered to give the 4-chloro-3-hydroxy-10H-phenothiazine (95%). m.p.: 110° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04666907 |
| 出典データセット | uspto-grants-1987_05 |
| ORD ID | ord-59864131e5c34b0582e817f322c40d52 |
| 出典メモ | uspto-grants-1987_05 |