化工社化工社 化学情報印刷レポート · 研究参考用
Water → chloromaleic acid N-[2-(2-methoxyphenyl)-ethyl]-imide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | Chloromaleic anhydride | HCID 66772 | — |
| 反応物 | 2-Methoxyphenethylamine | HCID 74896 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 生成物 | chloromaleic acid N-[2-(2-methoxyphenyl)-ethyl]-imide | HCID 178489456 | 78% |
反応手順
13.25 g (0.1 mol) of chloromaleic anhydride and 15.2 g (0.1 mol) of 2-(2-methoxyphenyl)-ethylamine are heated to the boiling point in 100 ml of glacial acetic acid for 4 hours. 100 ml of water are then added and the oil which has precipitated is extracted with methylene chloride. The methylene chloride phase is separated off, washed with water, dried and evaporated. The oil which remains crystallizes. 20.8 g (78% of theory) of chloromaleic acid N-[2-(2-methoxyphenyl)-ethyl]-imide are obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04666935 |
| 出典データセット | uspto-grants-1987_05 |
| ORD ID | ord-33887f723c6e4b00a2adcfa2a364aa5b |
| 出典メモ | uspto-grants-1987_05 |