Methanol → HCID 86741190、化合物

HRID 979827ノート

反応式

HRID 979827 の反応式
[NH2:1][C:2]1[CH:3]=[C:4]([CH3:15])[CH:5]=[C:6]2[C:11]=1[CH:10]([C:12]([OH:14])=[O:13])[CH2:9][CH2:8][CH2:7]2.S(=O)(=O)(O)O.[CH3:21]O>>[NH2:1][C:2]1[CH:3]=[C:4]([CH3:15])[CH:5]=[C:6]2[C:11]=1[CH:10]([C:12]([O:14][CH3:21])=[O:13])[CH2:9][CH2:8][CH2:7]2

参加物

4

反応物 3

HCID 887MethanolHCID 1118Sulfuric AcidHCID 202229738-Amino-6-methyl-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid

生成物 1

HCID 86741190HCID 86741190、化合物

実験手順

The product from Example 140 was dissolved in methanol (50 ml) and concentrated sulfuric acid (3 ml) was added. The reaction was refluxed for 4 hours and solvent was evaporated to one-half the volume. Following the procedure of Example 136 the desired ester was obtained.

後処理

  1. temperatureThe reaction was refluxed for 4 hours
  2. customsolvent was evaporated to one-half the volume
  3. customwas obtained

出典と根拠

ORDレコード
ord-bc8bd6742c584b9d9950feda87a49a66
出典データセット
uspto-grants-1987_01
特許番号
US04634705

反応ノート

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