Hydrogen Peroxide → 2,6-Pyridinedicarboxylic acid, 1-oxide

HRID 980129

反応式

HRID 980129 の反応式
[N:1]1[C:6]([C:7]([OH:9])=[O:8])=[CH:5][CH:4]=[CH:3][C:2]=1[C:10]([OH:12])=[O:11].[OH:13]O>O.[O-][W]([O-])(=O)=O.[Na+].[Na+]>[N+:1]1([O-:13])[C:2]([C:10]([OH:12])=[O:11])=[CH:3][CH:4]=[CH:5][C:6]=1[C:7]([OH:9])=[O:8]

参加物

5

反応物 2

HCID 784Hydrogen Peroxide2 回HCID 103672,6-Pyridinedicarboxylic acid

生成物 1

HCID 851792,6-Pyridinedicarboxylic acid, 1-oxide

試薬・触媒・溶媒 2

HCID 26052Sodium tungstate触媒HCID 962Water溶媒

反応条件

温度
90 °C

実験手順

50 g of pyridine-2,6-dicarboxylic acid was suspended in 275 g of water. 47 g of 30% hydrogen peroxide aqueous solution and 2.8 g of sodium tungstate were added to the resulting suspension. The suspension was heated to a temperature of 90° C. for 24 hours. As a result, the carboxylic acid as starting material was gradually dissolved in the aqueous solution during heating, and fresh crystals were then deposited. 24 g of 30% hydrogen peroxide aqueous solution was further added to the solution. The solution was heated for 12 hours and then allowed to cool to obtain 48 g of colorless prismatic creptais of pyridine-2,6-dicarboxylic acid N-oxide.

後処理

  1. dissolutionwas gradually dissolved in the aqueous solution
  2. temperatureduring heating
  3. temperatureThe solution was heated for 12 hours
  4. temperatureto cool

出典と根拠

ORDレコード
ord-1c23be193dda44799a3396c1dcc3f275
出典データセット
uspto-grants-1987_01
特許番号
US04636462

関連ノート

読み込み中…