Dimethylformamide → N-[[3-[4-(4-cyano-4-hydroxy-3,3-dimethylpiperidin-1-yl)-3-fluorophenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide

反応式

[CH3:31][N:32]([CH3:33])[CH:34]=[O:35].[K:28][C:29]#[N:30].[O:1]=[C:2]1[C:3]([CH3:26])([CH3:27])[CH2:4][N:5]([c:8]2[c:9]([F:25])[cH:10][c:11]([N:14]3[C:15](=[O:24])[O:16][CH:17]([CH2:19][NH:20][C:21]([CH3:22])=[O:23])[CH2:18]3)[cH:12][cH:13]2)[CH2:6][CH2:7]1>>[OH:1][C:2]1([C:29]#[N:30])[C:3]([CH3:26])([CH3:27])[CH2:4][N:5]([c:8]2[c:9]([F:25])[cH:10][c:11]([N:14]3[C:15](=[O:24])[O:16][CH:17]([CH2:19][NH:20][C:21]([CH3:22])=[O:23])[CH2:18]3)[cH:12][cH:13]2)[CH2:6][CH2:7]1

参加物

反応物 3

HCID 6228Dimethylformamide

HCID 68695641N-[[3-[4-(3,3-dimethyl-4-oxopiperidin-1-yl)-3-fluorophenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide

HCID 178511842HCID 178511842、化合物

生成物 1

HCID 87543162N-[[3-[4-(4-cyano-4-hydroxy-3,3-dimethylpiperidin-1-yl)-3-fluorophenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide

出典と根拠

ORDレコード: ord-8ef89ed6e30241788c92b92d26bfc5c8
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…