Acetic Acid → Phenoxybutylamine acetate

HRID 980868ノート

反応式

HRID 980868 の反応式
[O:1]([CH2:8][CH2:9][CH2:10][CH2:11][NH2:12])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C([N+]#[C-])CCC.[C:19]([OH:22])(=[O:21])[CH3:20]>CO>[C:19]([OH:22])(=[O:21])[CH3:20].[O:1]([CH2:8][CH2:9][CH2:10][CH2:11][NH2:12])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

参加物

5

反応物 3

HCID 176Acetic AcidHCID 76008Butyl isocyanideHCID 1162404-Phenoxybutan-1-amine

生成物 1

HCID 70062463Phenoxybutylamine acetate

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

In a three-necked flask of 25 ml provided with a magnetic bar, a calcium chloride tube and a dropping funnel, 1.99 gr (0.012 mol) of phenoxybutylamine, 1 gr (0.012 mol) of n-butylisonitrile and 0.72 gr of acetic acid were mixed in 5 ml of methanol. A precipitate of phenoxybutylamine acetate formed. This suspension cooled in an ice bath was added under good agitation with 0.87 gr (0.012 mol) of isobutyraldehyde.

後処理

  1. customIn a three-necked flask of 25 ml provided with a magnetic bar, a calcium chloride tube and a dropping funnel

出典と根拠

ORDレコード
ord-6736ed9f75254637a52481ecc0d7be4d
出典データセット
uspto-grants-1987_01
特許番号
US04639468

反応ノート

読み込み中…