Trifluoroacetic anhydride → HCID 20071767、化合物
反応式
[CH3:1][S:2]([C:4]1[CH:9]=[CH:8][C:7]([C:10](=[O:18])[CH:11]([CH3:17])[CH2:12][C:13]([O:15][CH3:16])=[O:14])=[CH:6][CH:5]=1)=O.[F:19][C:20]([F:31])([F:30])[C:21]([O:23]C(=O)C(F)(F)F)=[O:22]>>[F:19][C:20]([F:31])([F:30])[C:21]([O:23][CH2:1][S:2][C:4]1[CH:9]=[CH:8][C:7]([C:10](=[O:18])[CH:11]([CH3:17])[CH2:12][C:13]([O:15][CH3:16])=[O:14])=[CH:6][CH:5]=1)=[O:22]参加物
3
実験手順
A solution of the sulfoxide from Step C of this Example (10 g) in trifluoroacetic anhydride (50 ml) was heated at 45° C. for 25 minutes and the mixture was evaporated, and then coevaporated with toluene, to dryness to give the title compound as an oil (15 g, crude) which was used directly in the following step.
後処理
- customwas heated at 45° C. for 25 minutes
- customthe mixture was evaporated
出典と根拠
- ORDレコード
- ord-6676e588402743eda18ec160fd86ddfa
- 出典データセット
- uspto-grants-1991_02