HCID 20071767、化合物 → HCID 20071746、化合物
反応式
FC(F)(F)C(OC[S:7][C:8]1[CH:13]=[CH:12][C:11]([C:14](=[O:22])[CH:15]([CH3:21])[CH2:16][C:17]([O:19][CH3:20])=[O:18])=[CH:10][CH:9]=1)=O>CO.CCN(CC)CC>[SH:7][C:8]1[CH:9]=[CH:10][C:11]([C:14](=[O:22])[CH:15]([CH3:21])[CH2:16][C:17]([O:19][CH3:20])=[O:18])=[CH:12][CH:13]=1参加物
3
実験手順
To the neat trifluoroacetate from Step D of this Example (12.3 g) was added a mixture of 1:1 MeOH-NEt3 (600 ml) and the resulting reaction mixture was evaporated under vacuum. The procedure was repeated twice more. The residue was dissolved in CH2Cl2, washed with 1N HCl and brine and dried over Na2SO4. Evaporation of the solvent gave the title compound as an oil (7.8 g, 97%).
後処理
- customthe resulting reaction mixture
- customwas evaporated under vacuum
- dissolutionThe residue was dissolved in CH2Cl2
- washwashed with 1N HCl and brine
- dry with materialdried over Na2SO4
- customEvaporation of the solvent
出典と根拠
- ORDレコード
- ord-e46a4b2c1164441c8755e73ac85dd5ea
- 出典データセット
- uspto-grants-1991_02
- 特許番号
- US04990526
反応ノート
読み込み中…