Ethanol → HCID 14646898、化合物

HRID 981350

反応式

HRID 981350 の反応式
[OH-:1].[K+].[CH2:3]([OH:5])[CH3:4].[SH:6][C:7]1[S:8][C:9]([SH:12])=[N:10][N:11]=1.Br[CH:14]([CH2:18][C:19]([OH:21])=[O:20])[C:15]([OH:17])=[O:16]>O>[S:8]1[C:9]([S:12][CH:4]([CH2:14][C:15]([OH:17])=[O:16])[C:3]([OH:1])=[O:5])=[N:10][N:11]=[C:7]1[S:6][CH:14]([CH2:18][C:19]([OH:21])=[O:20])[C:15]([OH:17])=[O:16]

参加物

6

反応物 4

HCID 702Ethanol4 回HCID 14797Potassium Hydroxide2 回HCID 73557Bromosuccinic acidHCID 178418558HCID 178418558、化合物

生成物 1

HCID 14646898HCID 14646898、化合物

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

About 68 g. of a solution of 39.6 g. (0.6 mole) of KOH (85%) in 200 ml. of abs. ethanol is added to a stirred slurry of 15.0 g. (0.1 mole) of 2,5-dimercapto-1,3,4-thiadiazole in 80 ml. of abs. ethanol, at 10°-15° C. The resultant mixture is stirred at 10°-15° C. for half hour thereafter, a clear solution of 39.4 g. (0.2 mole) of bromosuccinic acid in 70 ml. of abs. ethanol is added dropwise over a period of 15 minutes at 10°-15° C. followed by the gradual addition of the remainder of the KOH solution at the same temperature range over a period of 15 minutes. After adding 100 ml. of abs. ethanol, the reaction mixture is stirred in the cooling bath for more than one hour, then overnight in water bath at ambient temperature.

後処理

  1. customat 10°-15° C
  2. additionAfter adding 100 ml
  3. customat ambient temperature

出典と根拠

ORDレコード
ord-4d86d0665c834e09a920b9983f2b6ec4
出典データセット
uspto-grants-1991_02
特許番号
US04990652

関連ノート

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