Ammonia → N1-[3-(Trifluoromethyl)phenyl]-1,3-propanediamine
反応式
[F:1][C:2]([F:15])([F:14])[C:3]1[CH:4]=[C:5]([NH:9][CH2:10][CH2:11][C:12]#[N:13])[CH:6]=[CH:7][CH:8]=1.N.[H][H]>[Ni].CO>[F:1][C:2]([F:14])([F:15])[C:3]1[CH:4]=[C:5]([NH:9][CH2:10][CH2:11][CH2:12][NH2:13])[CH:6]=[CH:7][CH:8]=1参加物
6
実験手順
A mixture of 13.6 parts of 3-[[3-(trifluoromethyl)phenyl]amino]propanenitrile and 400 parts of methanol saturated with ammonia was hydrogenated at normal pressure and at a temperature below 20° C. with 3 parts of Raney Nickel catalyst. After the calculated amount of hydrogen was taken up, the catalyst was filtered off and the filtrate was evaporated, yielding 13 parts (100%) of N1 -[3-(trifluoromethyl)phenyl]-1,3-propanediamine as a residue (int. 106).
後処理
- filtrationthe catalyst was filtered off
- customthe filtrate was evaporated
出典と根拠
- ORDレコード
- ord-ab14dc60e28b4dc8b4fba4c874ade40a
- 出典データセット
- uspto-grants-1991_02
- 特許番号
- US04992433
反応ノート
読み込み中…