Ammonia → HCID 20071066、化合物

HRID 981815ノート

反応式

HRID 981815 の反応式
Cl[C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[C:4]([NH:9][CH3:10])[C:3]=1[N+:11]([O-:13])=[O:12].[NH3:14]>O.C(O)C>[Cl:8][C:6]1[CH:5]=[C:4]([NH:9][CH3:10])[C:3]([N+:11]([O-:13])=[O:12])=[C:2]([NH2:14])[CH:7]=1

参加物

5

反応物 2

HCID 222AmmoniaHCID 20071071HCID 20071071、化合物

生成物 1

HCID 20071066HCID 20071066、化合物

試薬・触媒・溶媒 2

HCID 702Ethanol溶媒HCID 962Water溶媒

実験手順

0.034 mole (7.5 g) of 2,4-dichloro-6-methylaminonitrobenzene is added in an autoclave to 100 ml of a 28% strength solution of ammonia in water and 50 ml of ethanol. The reaction mixture is heated to 145°-150° C. for 12 hours, the pressure being 12 kg/cm2. After cooling, the expected product precipitates from the reaction mixture. After being filtered off and reslurried in water, it is dried hot under vacuum in the presence of phosphorus pentoxide. Recrystallized from isopropanol, it melts at 129° C.

後処理

  1. temperatureThe reaction mixture is heated to 145°-150° C. for 12 hours
  2. temperatureAfter cooling
  3. customthe expected product precipitates from the reaction mixture
  4. filtrationAfter being filtered off
  5. dry with materialit is dried hot under vacuum in the presence of phosphorus pentoxide
  6. customRecrystallized from isopropanol, it melts at 129° C.

出典と根拠

ORDレコード
ord-83c131031f14438284faf397fa7f4eb6
出典データセット
uspto-grants-1991_02
特許番号
US04992586

反応ノート

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