関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | Calcium Carbonate | HCID 10112 | — |
| 反応物 | 2-Chloro-3-nitropyridine | HCID 79613 | — |
| 反応物 | 2,4-Dimethylbenzene-1,3-diamine | HCID 4625581 | — |
| 生成物 | 2-[(3-Nitro-2,4-dimethylphenyl)-amino]-3-aminopyridine | HCID 20068349 | — |
反応手順
8.4 g of 2,4-diamino-m-xylene, 9.6 g of 2-chloro-3nitropyridine and 3.0 g of calcium carbonate were introduced into 300 ml water and the resulting mixture was heated under reflux for 8 hours to the boiling temperature. The reaction mixture was filtered while hot, the reaction product precipitating from the filtrate on cooling to 20° C. It was isolated and recrystallized from toluene. 6.2 g of the product melting at 173° to 175° C. were obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04994087 |
|---|
| 出典データセット | uspto-grants-1991_02 |
|---|
| ORD ID | ord-83d842d100b547959c007af42c3def27 |
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| 出典メモ | uspto-grants-1991_02 |
|---|
