3-Chloro-1-propanol → Butanoic acid, 3-oxo-, 3-chloropropyl ester
反応式
[Cl:1][CH2:2][CH2:3][CH2:4][OH:5].[CH2:6]=[C:7]1[O:11][C:9](=[O:10])[CH2:8]1>C(N(CC)CC)C>[C:9]([O:5][CH2:4][CH2:3][CH2:2][Cl:1])(=[O:10])[CH2:8][C:7]([CH3:6])=[O:11]参加物
4
実験手順
3-Chloropropanol (47.3 g, 0.500 mole) and a catalytic amount of triethylamine at 65° were treated dropwise with diketene (42 g, 0.50 mole). After the addition was complete, the reaction was stirred at 65° for an additional hour. Distillation of the residue furnished 72.9 g (82%) of 3-chloropropyl acetoacetate as a clear liquid, b.p. 78°-85° at 150 torr.
後処理
- additionAfter the addition
- distillationDistillation of the residue
出典と根拠
- ORDレコード
- ord-e767c309455343a9b54fc32afb1b4fcb
- 出典データセット
- uspto-grants-1991_02
- 特許番号
- US04994476
反応ノート
読み込み中…