1-[4-[(4-Fluorophenyl)methyl]phenyl]piperazine → 5-[2-(4-(4-(4-Fluorophenyl)methylphenyl)piperazin-1-yl)acetyl]-2,3,4,5-tetrahydro-1,5-benzoxazepine

HRID 982

反応式

HRID 982 の反応式
Br[CH2:2][C:3]([N:5]1[C:11]2[CH:12]=[CH:13][CH:14]=[CH:15][C:10]=2[O:9][CH2:8][CH2:7][CH2:6]1)=[O:4].[F:16][C:17]1[CH:22]=[CH:21][C:20]([CH2:23][C:24]2[CH:29]=[CH:28][C:27]([N:30]3[CH2:35][CH2:34][NH:33][CH2:32][CH2:31]3)=[CH:26][CH:25]=2)=[CH:19][CH:18]=1>>[F:16][C:17]1[CH:18]=[CH:19][C:20]([CH2:23][C:24]2[CH:29]=[CH:28][C:27]([N:30]3[CH2:31][CH2:32][N:33]([CH2:2][C:3]([N:5]4[C:11]5[CH:12]=[CH:13][CH:14]=[CH:15][C:10]=5[O:9][CH2:8][CH2:7][CH2:6]4)=[O:4])[CH2:34][CH2:35]3)=[CH:26][CH:25]=2)=[CH:21][CH:22]=1

参加物

3

反応物 2

HCID 15199981-[4-[(4-Fluorophenyl)methyl]phenyl]piperazineHCID 196942555-(2-Bromoacetyl)-2,3,4,5-tetrahydro-1,5-benzoxazepine

生成物 1

HCID 196942525-[2-(4-(4-(4-Fluorophenyl)methylphenyl)piperazin-1-yl)acetyl]-2,3,4,5-tetrahydro-1,5-benzoxazepine

実験手順

The compound (15) synthesized in Reference Example and the compound (5) synthesized in Reference Example were used to produce the above compound in the same way as Example 1.

後処理

  1. customto produce the above compound in the same way as Example 1

出典と根拠

ORDレコード
ord-29980035cd8743d88cbb26a64e2988b5
出典データセット
uspto-grants-1998_03
特許番号
US05723475

関連ノート

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